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. 1987 Sep 25;15(18):7235–7248. doi: 10.1093/nar/15.18.7235

Solid phase synthesis of oligoribonucleotides using the o-nitrobenzyl group for 2'-hydroxyl protection and H-phosphonate chemistry.

T Tanaka 1, S Tamatsukuri 1, M Ikehara 1
PMCID: PMC306245  PMID: 3658693

Abstract

Oligoribonucleotides with chain length of 7, 11, 15, 17, 24 and 34 were synthesized on long chain alkylamine controlled pore glass beads (LCA-CPG) using o-nitrobenzyl protection of 2'-hydroxyls via a H-phosphonate approach either manually or by using an automatic synthesizer. The oligoribonucleotides were obtained in yields of 0.6 0.6-20%, based on initial nucleoside bound to the LCA-CPG support.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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