Table 1.
Treatment | Lowest inhibitory dose (μg/mL) | Clinical dose for amebiasis (mg/kg per day) | Murine dosage (mg/kg) |
---|---|---|---|
Metronidazole | < 0.005 | 32.1 | 10.0 |
Tinidazole | < 0.005 | 28.6 | 10.0 |
Nitazoxanide | 0.02 | 14.3 | 10.0/20.0 |
Iodoquinol | 0.435 | 27.9 | 55.7 |
Chloroquine (base) | > 2.143 | 8.6 | 17.1 |
Emetine | 0.058 | 0.09 | 1.9 |
Pyrvinium pamoate | 0.117 | 7.5* | 15.0 |
AMIX | < 0.005 | N/A | 10.0 |
VPC16a1006 | 0.02 | N/A | 10.0 |
Antihelminthic dose in micrograms per kilogram.