Table 1.
Ocular Involvement in Guinea Pigs With Systemic Tuberculosis
| Animal No. | Granulomatous Inflammation | Location | AFB | qPCR |
|---|---|---|---|---|
| CDC1 | ||||
| OD | No | NA | No | ND |
| OS | Yes | Choroid | No | 287a |
| CDC 2 | ||||
| OD | Yes | Choroid | No | 315a |
| OS | No | NA | No | ND |
| CDC 3 | ||||
| OD | No | NA | No | ND |
| OS | Yes | Choroid | Yes | 1244a |
| CDC 4 | ||||
| OD | Yes | Choroid | No | ND |
| OS | No | NA | No | ND |
| H37Rv 5 | ||||
| OD | No | NA | No | ND |
| OS | Yes | Limbus | Yes | 883a |
| H37Rv 6 | ||||
| OD | No | NA | No | ND |
| OS | No | NA | No | ND |
Abbreviations: AFB, acid-fast bacilli (detected by acid-fast stain); CDC, Mycobacterium tuberculosis CDC1551; H37Rv, M tuberculosis H37Rv; NA, not applicable; ND, not detected; OD, right eye; OS, left eye; qPCR, quantitative polymerase chain reaction.
a
Mycobacterial genome load per 1 μg of total tissue DNA.