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. Author manuscript; available in PMC: 2011 Mar 22.
Published in final edited form as: Bioorg Med Chem Lett. 2009 Mar 24;19(14):3919–3923. doi: 10.1016/j.bmcl.2009.03.072

Table 2.

Binding affinities (M–1) for polyamides

5′-ATGGTT-3′ 5′-ATGGTA-3′ 5′-ATGGTC-3′ 5′-ATGGTG-3′
1 2.1 (±0.6)× 108 2.0 (±0.5) × 108 <107 <107
2R 1.6 (±0.7) × 109 1.7 (±0.9) × 109 3.9 (±2.0) × 107 <107
4R 3.3 (±0.1} × 109 1.8 (±0.2) × 109 5.0 (±1.1) × 107 <107
4S 1.1 (±0.1) × 109 1.3 (±0.2) × 109 6.0 (± 0,4) × 107 <107
3R 3.2 (±0.4) × 108 2.1 {±0.3) × 108 <107 <107
5R 2.0 (±0.4) × 109 5.2 (±1.6) × 108 8.9 (±2.8) × 107 <107

Equilibrium association constants are reported as mean values from three DNase I footprinting titration experiments. Standard deviations are shown in parentheses.