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. Author manuscript; available in PMC: 2011 Mar 22.
Published in final edited form as: Ann N Y Acad Sci. 2010 Jan;1184:e1–20. doi: 10.1111/j.1749-6632.2010.05432.x

Figure 4.

Figure 4

Dg and Dys mutants manifest age-dependent muscle degeneration. Light microscopy of histological transverse sections of IFMs stained with H&E. (I–K) The mesoderm-specific RNAi-based reduction of Dg and Dys (dsDys C-term and dsDg30A/24B-Gal4) at 20 days after eclosion, but not at 3 days after eclosion (I) show obvious IFM muscle pathology: the loss of fiber density and vacuolization (asterisks). Reproduced with permission from Ruohola-Baker et al.