Table 1.
Histology | Measurements at Round Window | Frequency Range of Initial Damage |
Depth First Damage Detected |
Final Thresholds |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Animal | Ear | Site of Damage |
Breach of Scala Media |
CM CF (Hz) |
CM Thresh. (dB SPL) |
CAP CF (Hz) |
CAP Thresh. (db SPL) |
Maximum Depth Traveled (mm)* |
CM | CAP | CM (mm)* |
CAP (mm)* |
CM (db SPL) |
CAP (db SPL) |
Recovery after Retraction |
Gerbil #11 |
Right | OSL-BM | yes | 8k | 22 | 8k | 27 | 1800 | mid | high | 1000 | 1000 | 48 | >63 | no |
Gerbil #13 |
Right | BM | yes | 8k | 9 | 8k | 13 | 1000 | mid | high | 750 | 500 | 51 | >63 | no |
Gerbil #14 |
Left | BM | yes | 4k | 18 | 8k | 15 | 1950 | high | high | 1700 | 1300 | 37 | >63 | no |
Gerbil #15 |
Right | BM | yes | 4k | 23 | 4k | 37 | 400 | mid | low | 400 | 250 | >72 | >72 | no |
Gerbil #18 |
Right | OSL | no | 4k | 16 | 4k | 16 | 550 | none | low | none | 550 | 17 | 21 | incomplete |
Gerbil #21 |
Right | BM | yes | 4k | 13 | 4k | 21 | 700 | high | high | 700 | 700 | 33 | 54 | no |
Gerbil #22 |
Right | None | no | 4k | 6 | 4k | 15 | 700 | none | low | none | 650 | 6 | 9 | complete |
Gerbil #24 |
Right | BM | no | 4k | 12 | 4k | 22 | 500 | none | high | none | 500 | 15 | 31 | no |
Gerbil #27 |
Right | BM | no | 4k | 11 | 4k | 29 | 400 | high | high | 400 | 400 | 8 | 29 | no |
Gerbil #27 |
Left | OSL-BM | no | 4k | 13 | 4k | 20 | 550 | high | high | 600 | 550 | 19 | 41 | no |
all insertion depths were measured from the round window (via the micromanipulator)
Abbreviations: CM: cochlear microphonics, CAP: compound action potential, OSL: osseous spiral lamina, BM: basilar membrane