Table 3. Clinical characteristics of non-autoimmune preeclampsia patients with complement regulatory protein mutations.
| Mutation/Variant | Maternal Age (y) | Preeclampsia | GA at Delivery (wk) | Fetal Weight in Grams (Percentile weight for GA) |
| MCP/A304V | 24 | Severe | 33 | 2,102 (27) |
| MCP/A304V | 23 | Severea | 34 | 2,807 (48) |
| MCP/A304V | 41 | HELLPb | 22 | Neonatal demise |
| MCP/A304V | 33 | Severec | 33 | 2,013 (22) |
| CFI/I398L | 24 | Severed | 37 | 2,940 (35); 2,145 (2) |
All patients were white.
a
Previous pregnancy preeclampsia delivered at 36 wk.
b
Pregnancy complicated by sphenoid sinus thrombosis; thrombophilia evaluation negative; four normal previous pregnancies; history of idiopathic thrombocytopenia purpura; mother with SLE.
c
Oligohydramnios.
d
Twins.
GA, gestational age.