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. 2011 Mar 22;6(3):e18059. doi: 10.1371/journal.pone.0018059

Figure 3. Abnormal chondrocyte differentiation in the growth plate of Slc39a14-KO mice.

Figure 3

(A) In situ hybridization analysis for Slc39a14 in an embryo at 16.5 dpc, and magnified images of the limb (1), spine (2), and thorax (3). Green arrowheads indicate Slc39a14 expression. (B and C) In situ hybridization analysis for Slc39a14, Col2a1, Ihh, and Col10a1 in the growth plates from 4-week-old control (Ctrl) and Slc39a14-KO mice. (D) Col10a1 levels in control (Ctrl) and Slc39a14-KO chondrocytes. Data represent the mean ± S.D. (**P<0.01). (E) H&E staining of the growth plates from control (Ctrl) and Slc39a14-KO mice (4-week-old).