Table 5.
Characteristics of the five included 18F-FDG PET studies
| Study (year, reference) |
County | No. of patients | Time of fasting before scanning |
FDG dose, time interval between FDG administration and scanning |
Attenuation correction, reconstruction method |
Interpreter(s) | Reference standard |
|---|---|---|---|---|---|---|---|
| Lim 2006 [34] | South Korea | 124 | 4h | 370-555 MBq, 60 min |
Yes, order subset expectation maximization |
Two experienced nuclear medicine physicians |
Surgical and histopathologic standards |
| Yoshioka 2003 [35] | United States | 20 | 4 h | Mean 222 MBq, 30 min |
Yes, NCD | Three PET specialists | CT, cytology, and clinical course |
| Yoshioka 2003 [35] | United States | 22 | 4 h | Mean 222 MBq, 45 min |
Yes, NCD | Three PET specialists | CT, cytology, and clinical course |
| Chen 2005 [36] | United States | 68 | 4 h | 370-555 Mbq, 60 min |
Yes, iterative | Two experienced nuclear medicine physicians |
Surgical and histological classification |
| Yun 2005 [41] | United States | 81 | 4 h | 370 MBq, 60 min |
Yes, iterative | Two experienced nuclear medicine physicians | Histopathologic examination |
| Yeung 1998 [42] | United States | 23 | 6 h | 370 MBq, 45 min to 1 h |
Yes, NCD | An experienced PET reader |
Histology, surgical findings, clinical follow-up |
NCD: not clearly described.