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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Exp Gerontol. 2010 Nov 21;46(4):282–291. doi: 10.1016/j.exger.2010.11.004

Table 2.

Protein and mRNA expression of conventional MHC isoforms in young (8 month) and old (26 month) muscles with different origins and functions. Extraocular (EOM); Masseter (M); Posterior digastric (PD); Geniohyoid (GH); Styloglossus (SG) and Biceps brachii (BB).

Function BRANCHIAL ARCH SOMITIC
Eye
Mastication
Mastication
Locomotion
EOM M PD GH SG BB P
Vision Jaw Closer Jaw Opener Hyoid Elevation Tongue Retrusion Stability/Locomotion Stability/Locomotion

MHC composition by protein analysis
EOM M PD GH SG BB P
Y O Y O Y O Y O Y O Y O Y O
IIb 47%±5% 56%±7% 51%±14% 48%±9% 35%±10% 33%±5% 49%±5% 50%±7% 29%±5% 25%±6% 61%±7% 53%±12% 60%±13% 62%±11%
IIx 27%±3% 27%±6% 35%±8% 37%±5% 39%±5% 41%±3% 34%±4% 34%±5% 43%±6% 43%±4% 26%±4% 31%±7% 29%±8% 24%±6%
IIa 17%±4% 12%±3% 13%±7% 14%±5% 20%±6% 23%±3% 15%±2% 16%±3% 27%±4% 32%±2% 10%±4% 13%±5% 9%±5% 10%±5%
I 9%±5% 6%±4% 1%±1% 1%±1% 6%±3% 3%±2% 2%±2% 0%±1% 1%±2% 1%±1% 3%±1% 3%±1% 2%±2% 3%±2%
“Fast” 0.63 0.26 −0.26 −0.65 0.67 0.23 −1.27 −1.36 1.22 0.62
Factor Score 0.457 −0.466 0.448 −1.309 0.922

MHC composition by mRNA analysis
EOM M PD GH SG BB
Y(n=1) O(n=1) Y O Y O Y O Y O Y O
IIb 46% 59% 59%±16% 62%±6% 36%±6% 26%±9% 69%±12% 63%±6% 33%±10% 44%±12% 71%±9% 68%24%
IIx 30% 21% 39%±14% 37%±7% 46%±6% 42%±9% 24%±10% 27%±14% 52%±10% 42%±9% 21%±5% 28%±19%
IIa 12% 5% 2%±2% 1%±1% 11%±5% 13%±4% 8%±2% 8%±2% 14%±2% 13%±2% 5%±3% 3%±3%
I 12% 15% 0%±0% 0%±1% 7%±3% 20%±13% 0%±0% 2%±1% 2%±2% 2%±2% 3%±2% 2%±2%