Table 4.

Cumulative effects of risk factors on poor outcome by domain.^a

Baseline risk factor	CPG grades I–III at 12 months (%)	CPG grade IVb at 12 months (%)	Adjusted RR	Adjusted PAF (%)
Symptom severity
Neither high pain nor functional disability	57	9	1.00
High pain only	22	17	3.10	11.8
High functional disability only	6	1	1.43	0.4
High pain and functional disability	15	72	6.90	62.0
Total				74.2
Widespread pain
Neither leg nor upper body pain	13	1	1.00
Leg pain only	17	7	1.91	3.5
Upper body pain only	25	13	3.06	8.8
Leg and upper body pain	45	78	3.75	57.4
Total				69.6
Pain affect
Neither anxious nor depressed	67	20	1.00
Anxious only	16	23	1.80	10.3
Depressed only	6	9	1.47	2.8
Anxious and depressed	12	48	2.34	27.4
Total				40.4
Pain cognitions
Not catastrophising nor fear-avoidance	69	32	1.00
Catastrophising only	11	29	1.24	5.7
Fear-avoidance only	11	3	0.46	−3.4
Catastrophising and fear-avoidance	8	36	1.40	10.4
Total				12.7

^aFor domains with more than two risk factors.

^bDefined as poor outcome.