Table 2.
Baseline substance use history, N=374.
| Variable (N, if not complete cohort) | Female N=92 | Male N=282 | p-value |
|---|---|---|---|
| Tobacco use | <0.0001 | ||
| Current | 56 (60.9) | 242 (85.8) | |
| Ex-smoker | 9 (9.8) | 28 (9.9) | |
| Never smoker | 27 (29.4) | 12 (4.3) | |
| Pack-years, N=319 | 10.7 ± 9.9 | 20.8 ± 17.4 | <0.0001 |
| Drug use disorder (DSM-IV) | 0 (0) | 7 (2.5) | 0.34 |
| Drug use disorder (year) | 0 (0) | 2 (0.7) | 1.00 |
| Drug use disorder (lifetime) | 0 (0) | 23 (8.2) | 0.002 |
| AUDIT score (mean ± STD) N=364 | 8.6 ± 9.0 | 14.7 ± 8.7 | <0.0001 |
| Frequency alcohol consumption, past year, N=372 | <0.0001 | ||
| Nearly every day | 5 (5.5) | 57 (20.2) | |
| 3–4 days per week | 6 (5.5) | 44 (15.6) | |
| 1–2 days per week | 8 (8.8) | 50 (17.7) | |
| 1–3 days per month | 18 (19.8) | 60 (21.3) | |
| Less than once a month | 27 (29.7) | 33 (11.7) | |
| Did not drink in past year | 27 (29.7) | 37 (13.1) | |
| Average standard drinks on drinking days, N=373 | 4.4 ± 9.4 | 12.7 ± 15.0 | <0.0001 |
| Alcohol use disorder, any (past year) | 16 (17.4) | 112 (39.7) | <0.0001 |
| Alcohol dependence | 9 (9.8) | 74 (26.2) | 0.0008 |
| Alcohol abuse | 7 (7.6) | 38 (13.5) | 0.14 |
| Alcohol use disorder, any (lifetime) | 26 (28.3) | 199 (70.6) | <0.0001 |
| Alcohol dependence | 12 (13.0) | 94 (33.3) | 0.0001 |
| Alcohol abuse | 14 (15.2) | 105 (37.2) | <0.0001 |