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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: J Am Chem Soc. 2010 Nov 9;132(47):17015–17022. doi: 10.1021/ja107552s

Figure 3.

Figure 3

Relative rescue scores for the top 15 compounds, which (at 100 μM) reduced the toxicity of Aβ42 to PC12 cells. Viability of cells in the absence of Aβ or exogenous compounds was scaled (A570-670 = 0.716) to 100% and viability of cells exposed to Aβ42 alone (A570-670 = 0.496) was scaled as 0%. As shown in gray, compound 2002-H20 increased viability by 41%. Cell viability was assayed using the MTT assay. Compound identities and toxicity data for all 79 compounds provided in Supporting Information.

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