Figure 5.
Dose-dependence of compound 2002-H20’s ability to rescue PC12 cells from Aβ42-induced toxicity. 100% rescue scaled as the absorbance difference of cells incubated in buffer without peptide (A570–670 = 0.976) and 0% as absorbance difference of cells with 20 μM Aβ42 and no 2002-H20 (A570–670 = 0.389). An asterisk (*) indicates statistical significance as determined by the two-tailed Student’s T-test (p < 0.05) and error bars reflect standard error from the average of three measurements.