Figure 7.
Compound 2002-H20 increases amyloid fibril formation of synthetic Aβ42. (a) Congo red spectral shift. (b) Transmission electron microscopy. For both experiments, 20 μM of synthetic Aβ42 was incubated with the indicated concentration of compound 2002-H20. Incubations were at 37°C with gentle agitation for 24 hours.