Figure 1.
Structures of cyt P450cam and substrates. A) Structure of the cyt P450cam-CO-camphor complex in the immediate vicinity of the CO ligand (PDB entry 1T87). Shown are the heme, the CO distal ligand, the Cys357 proximal ligand, the bound camphor substrate, and several residues of helix I, which forms one wall of the active site. B) Structures of substrates whose complexes with cyt P450cam were investigated with 2D IR vibrational echo spectroscopy.