Table 1. Non-gonadotropin protein profile identified in u-hCG products.
N | Identified human proteins | Accession number | u-hCG manufacturer A | u-hCG manufacturer B |
1 | Major prion protein | P04156 | X | X |
2 | Apolipoprotein D | P05090 | X | X |
3 | Beta-2-glycoprotein 1 | P02749 | X | X |
4 | Complement decay-accelerating factor | P08174 | X | X |
5 | Alpha-1-microglobulin (protein AMBP) | P02760 | X | X |
6 | CD59 glycoprotein | P13987 | X | X |
7 | Uromodulin | P07911 | X | X |
8 | Growth/differentiation factor 15 | Q99988 | X | X |
9 | Endosialin | Q9HCU0 | X | X |
10 | Protein delta homolog 1 | P80370 | X | X |
11 | Fibrillin-1 | P35555 | X | X |
12 | Matrix metalloproteinase-9 | P14780 | X | X |
13 | Plasminogen | P00747 | X | |
14 | Complement factor B | P00751 | X | |
15 | Tumor necrosis factor receptor superfamily member 1B | P20333 | X | |
16 | Hepatocyte growth factor activator | Q04756 | X | |
17 | EGF-containing fibulin-like extracellular matrix protein 1 | Q12805 | X | |
18 | Tumor necrosis factor receptor superfamily member 1A | P19438 | X | |
19 | Connective tissue growth factor | O18739 | X | |
20 | Basement membrane-specific heparan sulfate proteoglycan core protein | P98160 | X | |
21 | Plasma serine protease inhibitor (protein C inhibitor) | P05154 | X | |
22 | Insulin-like growth factor-binding protein 7 | Q16270 | X | |
23 | Zinc-alpha-2-glycoprotein | P25311 | X | |
24 | Folate receptor alpha | P15328 | X | |
25 | Kininogen-1 | P01042 | X | |
26 | Protein S100-A7 (Psoriasin) | P31151 | X | |
27 | Pro-epidermal growth factor | P01133 | X | |
28 | Fibulin-2 | P98095 | X | |
29 | Collagen alpha-1(III) chain | P02461 | X | |
30 | Apolipoprotein(a) | P08519 | X | |
31 | Probable carboxypeptidase PM20D1 | Q6GTS8 | X | |
32 | Complement factor H-related protein 1 | Q03591 | X | |
33 | Cystatin-M | Q15828 | X |
u-hCG = urinary human chorionic gonadotropin.