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. 2011 Mar 23;6(3):e17815. doi: 10.1371/journal.pone.0017815

Table 2. Non-gonadotropin protein profile identified in hMG-HP products.

N Identified impurities Accession number hMG-HP manufacturer A Product 1 hMG-HP manufacturer A Product 2
1 Plasma serine protease inhibitor (protein C inhibitor) P05154 XX XX
2 Apolipoprotein D P05090 XX XX
3 Insulin-like growth factor-binding protein 7 Q16270 XX XX
4 Leukocyte elastase inhibitor P30740 XX XX
5 Alpha-2-antiplasmin P08697 XX X
6 Zinc-alpha-2-glycoprotein P25311 X XX
7 Serum albumin P02768 X X
8 Folate receptor alpha P15328 X X
9 Urokinase plasminogen activator surface receptor Q03405 X X
10 Afamin P43652 X X
11 Kininogen-1 P01042 X X
12 Reversion-inducing cysteine-rich protein with Kazal motifs O95980 X X
13 Alpha-1-antitrypsin P01009 X X
14 Plasminogen P00747 X X
15 Beta-2-glycoprotein 1 P02749 X X
16 Thrombospondin type-1 domain-containing protein 4 Q6ZMP0 X X
17 Protein S100-A7 (Psoriasin) P31151 X X
18 Alpha-1-acid glycoprotein 1 P02763 X X
19 Complement decay-accelerating factor P08174 X X
20 Sialate O-acetylesterase Q9HAT2 X
21 Alpha-1-microglobulin (protein AMBP) P02760 X
22 Ig kappa chain C region P01834 X
23 Ig gamma chain C region P01857 X
24 Peptidoglycan recognition protein O75594 X
25 Golgi phosphoprotein 2 Q8NBJ4 X
26 Delta-like protein 1 O00548 X
27 Death-associated protein kinase 1 P53355 X
28 CD27 antigen P26842 X
29 Serotransferrin P02787 X
30 TNF receptor superfamily member 21 O75509 X
31 CD59 glycoprotein P13987 X
32 Folate receptor gamma P41439 X
33 Platelet endothelial aggregation receptor 1 Q5VY43 X
34 TNF receptor superfamily member 4 P43489 X

hMG-HP  =  highly purified urinary human menopausal gonadotropin.