Figure 2. Relationship between the oxidative stress ratio (F-2 isoprostanes/Vitamin C concentrations, Ln transformed) and leukocyte telomere length (in base pairs, bp).

Filled circles represent depressed subjects (“MDD”) (F =  6.04, p<0.01, controlling for age and sex), and open squares represent controls (“Cont”) (F =  4.38, p<0.05, controlling for age and sex). In the combined sample (depressed plus controls), the relationship was also statistically significant (F =  8.21, p<0.001, controlling for age and sex).