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. 2001 Feb 27;98(6):3214–3219. doi: 10.1073/pnas.051625998

Figure 7.

Figure 7

MIS inhibits the growth of the human ovarian tumor cell line IGROV-1 in vivo. (A) The mean graft-size-ratio (GSR) +/− the SEM of the IGROV-1 tumors in the animals producing bioactive MIS (n = 8) was significantly smaller than the tumors exposed to bioinactive MIS (n = 10) (P = 0.016). A GSR of 1 indicates no net growth. (B) The mean GSR of the IGROV-1 tumors implanted in animals with MIS-producing CHO-B9 polymer (n = 30) was significantly smaller than the IGROV-1 tumors in the animals with empty polymer (n = 30) (P < 0.001).