Fig. 3. TNF-4.0 h-induces activation of GSK3β.
Lung lysate is assessed for phospho-GSK3α-Ser21, GSK3α, phospho-GSK3β-Ser9 and GSK3β in the Control (N=14), TNF-4.0 h (N=6), SB216763 (N=6) and SB216763+TNF-4.0 h (N=6) groups. A representative Western blot is shown. The data is expressed as GSK3α/β activation (Relative Density Units [RDU] ratio) derived from GSK3α/phospho-GSK3α-Ser 21and GSK3β/phospho-GSK3β-Ser9.
*= different (P< 0.05) from the Control group using the ANOVA with Holm-Sidak post-hoc multiple comparison test.