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Intracerebroventricular injection of kisspeptin-10 reduces the food intake response to an overnight fast in mice. Animals deprived of food for 17 h were ICV injected with kisspeptin-10 (0.3, 1 or 3 µg/mouse) or vehicle at 9 am and food ingestion was automatically recorded for 24 h and expressed as (a) food intake/1 h periods during the first 4 h, (b) food intake/4 h periods over 24 h and (c) cumulative food intake over 24 h. *P<0.05 and **P<0.01 vs. vehicle.
