Table 3.
Summary of Treatment Related Adverse Events
| Total | Grade ≥3 | |||
|---|---|---|---|---|
| No. | % | No. | % | |
| Constitutional | ||||
| Fatigue | 9 | 26 | 4 | 11 |
| Dehydration | 2 | 6 | 1 | 3 |
| Anorexia | 1 | 3 | 0 | |
|
| ||||
| Gastrointestinal | ||||
| Mucositis | 2 | 6 | 1 | 3 |
| Xerostomia | 1 | 3 | 0 | |
| Diarrhea | 9 | 26 | 6 | 17 |
| Nausea/Vomiting | 3 | 9 | 0 | |
| Dysphagia | 1 | 3 | 0 | |
| Odynophagia | 2 | 6 | 1 | 3 |
| GI Bleed | 5 | 14 | 2 (1 grade 5) | 6 |
| Ulcer | 1 | 3 | 0 | |
|
| ||||
| Dermatologic | ||||
| Hand/Foot Syndrome | 9 | 26 | 6 | 17 |
|
| ||||
| Pulmonary | ||||
| Hemoptysis | 2 | 6 | 0 | |
|
| ||||
| Cardiovascular | ||||
| Hypertension | 1 | 3 | 0 | 0 |
| Supraventricular Tachycardia | 2 | 6 | 2 | 6 |
|
| ||||
| Hemeatologic | ||||
| Leukopenia | 11 | 31 | 11 | 31 |
| Neutropenia | 12 | 34 | 12 | 34 |
| Anemia | 2 | 6 | 2 | 6 |
| Thrombocytopenia | 1 | 3 | 1 | 3 |
|
| ||||
| ENT | ||||
| Epistaxis | 2 | 6 | 0 | |
| Edema of Larynx | 1 | 3 | 1 | 3 |
|
| ||||
| Endocrine | ||||
| Hypocalcemia | 1 | 3 | 1 | 3 |
|
| ||||
| Neurologic | ||||
| Peripheral Neuropathy | 1 | 3 | 1 | 3 |
| Infection | 2 | 6 | 1 | 3 |
Grade 3 and higher are reported in separate column
Abbreviations: ENT, ear, nose, and throat