TABLE I.
Baseline Clinical Evaluation Characteristics of BeS and CBD Cases Stratified by Smoking Status
| Never smokers | Ever smokers | |||||
|---|---|---|---|---|---|---|
| BeS (n = 83) | CBD (n = 81) | P-value | BeS (n = 146) | CBD (n = 90) | P-value | |
| Age at diagnosis (years) | 50 (34.5–83) | 50.3 (27–74) | 1 | 53 (26–79) | 54.8 (32–80) | 0.37 |
| Gender (M/F) | 56 (67.5%)/27 (34.2%) | 63 (77.8%)/18 (22.2%) | 0.14 | 121 (82.9%)/25 (17.1%) | 81 (90.0%)/9 (10.0%) | 0.12 |
| Race (%) | 0.01 | 0.43 | ||||
| White | 64 (84.2%) | 77 (96.2%) | 124 (93.2%) | 85 (96.6%) | ||
| African American | 8 (10.5%) | 3 (3.8%) | 4 (3.0%) | 2 (2.3%) | ||
| Other | 4 (5.3%) | 0 (0.0%) | 5 (3.8%) | 1 (1.1%) | ||
| Industry (%) | 0.002 | <0.0001 | ||||
| Ceramics | 1 (1.3%) | 10 (12.5%) | 3 (2.1%) | 12 (13.3%) | ||
| Nuclear/aerospace | 51 (63.7%) | 32 (40.0%) | 73 (51.0%) | 23 (25.6%) | ||
| Recycling | 8 (10.0%) | 7 (8.7%) | 12 (8.4%) | 12 (13.3%) | ||
| Nuclear weapons | 20 (25.0%) | 55 (38.5%) | 55 (38.5%) | 43 (47.8%) | ||
| TreatmentaY/N | 0 (0.0%) | 10 (12.3%) | —b | 0 (0.0%) | 23 (25.5%) | —b |
| Years from first Be exposure to last exposure | 18 (2–50) | 20 (0–43) | 0.68 | 21 (0–55) | 22 (0–44) | 0.37 |
| Years from first Be exposure to diagnosis | 11.5 (0–40) | 13 (0–36) | 0.45 | 14 (0–39) | 16.5 (1–36) | 0.23 |
| Years from last exposure to diagnosis | 1.7 (0–44) | 1.7 (0–35) | 0.69 | 3.7 (0–50) | 1.5 (0–43) | 0.32 |
| Job | 0.002 | 0.45 | ||||
| Machinist | 4 (4.9%) | 17 (21.0%) | 25 (17.1%) | 19 (21.1%) | ||
| Non-machinist | 78 (95.1%) | 64 (79.0%) | 121 (82.9%) | 71 (78.9%) | ||
| Job type | 0.0004 | 0.01 | ||||
| Bystander | 23 (28.7%) | 7 (8.6%) | 26 (17.8%) | 7 (7.8%) | ||
| Dust disturber | 17 (21.3%) | 13 (16.1%) | 40 (27.4%) | 17 (18.9%) | ||
| Non-production | 25 (31.3%) | 25 (30.9%) | 33 (22.6%) | 19 (21.1%) | ||
| Production | 15 (18.7%) | 36 (44.4%) | 47 (32.2%) | 47 (52.2%) | ||
Data presented are medians (ranges) or frequencies (percentages).
Oral prednisone, methotrexate, pentoxifylline.
Zero values; no statistical analysis.