TABLE IV.

Additional Effects of Covariates Relative to Estimates Presented in Table III

	Decade of first exposure			Industry type			Ageb	Heightc	Sex	Race
	Pre-1970	1980s	1990-current	Ceramics	Aerospace	Recycling	—	—	Female	Black	Other
Pulmonary function
FVC (L)	0.28*	−0.275*	−0.38*	0.06	−0.10	0.06	−0.03*	0.12*	−0.75*	−0.61*	−0.35*
FEV1 (L)	0.19	−0.13	−0.25	−0.13	−0.03	0.09	−0.02*	0.08*	−0.58*	−0.44*	−0.25*
FEV1/FVC (%)	−0.44	0.88	−0.11	−4.88**	1.43**	0.87**	−0.02	−0.17	0.64	0.97	0.98
TLC (L)	0.15	0.13	0.28	0.23	−0.09	−0.23	−0.01	0.14*	−0.97*	−0.88*	−0.52*
DLCO (ml/min/mm Hg)	10.4*	−4.4*	−13.3*	0.25	−1.45	−2.50	−0.24*	0.48*	−7.29*	—	—
Exercise physiology
Max workload (W)	−6.1	−4.2	−8.0	−5.92	−11.01	1.92	−1.66*	3.50*	−57.9*	—	—
VO2 at maximal exercise (L/min)	0.16	−0.04	−0.27	0.04	−0.11	−0.11	−0.02*	0.04*	−0.63*	—	—
PaO2 at rest (mm Hg)	−4.1*	−3.5*	−1.4*	−1.9	−2.9	−1.9	−0.09**	—	—	—	—
PaO2 at maximal exercise (mm Hg)	2.9	−3.4	−1.1	−3.6**	−2.1**	−8.3**	0.06	—	—	—	—
(A-a)PaO2 at rest (mm Hg)	2.4	0.8	−1.7	3.1	0.6	0.3	0.09	—	—	—	—
(A-a) PaO2 at maximal exercise (mm Hg)	−1.1	0.1	−3.2	1.7	1.7	5.5	−0.06	—	—	—	—
Blood and BAL fluid markers
Peak blood BeLPTa	7.8*	−2.0*	−3.6*	−1.3	0.01	0.3	—	—	—	—	—
Peak BAL BeLPTa	2.7	2.1	−2.3	11.0*	0.3*	2.1*	—	—	—	—	—
BAL lymphocyte (%)	7.6	−3.0	−10.9	15.7*	−1.5*	−0.6*	—	—	—	—	—
WBC/CCa	3.0	−2.9	−7.2	10.3**	0.05**	0.8**	—	—	—	—	—

These effects are not time dependent (except for BeLPT and WBC/CC variables, which were analyzed on the natural log scale) and can be added to 10 and 30-year estimates in Table III.

^*P < 0.05 for effect of variable (relative to effect for subjects with characteristics in Table III).

^**P < 0.1 for effect of variable (relative to effect for subjects with characteristics in Table III).

^aEstimates were calculated at 25 years after first exposure.

^bAdd/subtract tabled amount for each year above/below 52 years of age.

^cAdd/subtract tabled amount for each inch above/below 68 inches of height.