Table 2.
Performance data (mean and standard deviation, SD) on placebo and pramipexole in controls (n = 18) and stimulant-dependent individuals (n = 18)
| Group | Healthy control | Stimulant-dependent | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | F (drug) | P (drug) | F (group) | P (group) | F (drug × group) | P (drug × group) | |
| SWM-placebo | 17.67 | 21.40 | 31.94 | 16.21 | 0.50 | 0.484 | 10.14 | 0.003 | 0.06 | 0.811 |
| SWM- pramipexole | 15.56 | 13.05 | 37.06 | 17.33 | ||||||
| DS-placebo | 7.72 | 2.52 | 5.61 | 1.79 | 0.89 | 0.353 | 5.00 | 0.033 | 1.07 | 0.308 |
| DS-pramipexole | 8.06 | 2.75 | 5.67 | 2.47 | ||||||
| RVIP-placebo | 0.96 | 0.03 | 0.91 | 0.04 | 2.66 | 0.113 | 11.57 | 0.002 | 0.18 | 0.672 |
| RVIP-pramipexole | 0.95 | 0.03 | 0.90 | 0.05 | ||||||
| PAL-placebo | 4.94 | 4.17 | 11.56 | 10.40 | 3.31 | 0.078 | 12.04 | 0.002 | 0.47 | 0.499 |
| PAL-pramipexole | 6.94 | 8.23 | 19.44 | 15.52 | ||||||
| IST-placebo | 10.58 | 3.28 | 9.27 | 4.50 | 0.35 | 0.560 | 3.71 | 0.063 | 6.67 | 0.015 |
| IST-pramipexole | 11.79 | 3.21 | 8.62 | 4.48 | ||||||
Task (dependent variable): SWM (total errors), DS digit-span (number), RVIP (A’), PAL (total errors), IST (number of boxes opened)