Fig. 2.
Effect of succinate and glutamate on hNaDC3. a Current-voltage (I-V) relations as a function of membrane potential (Vc) in hNaDC3-expressing oocytes were obtained by substraction of the currents in the presence of 1 mM succinate in ORI (●) or of 1 mM glutamate (○) in ORI from those measured in ORI alone. Data present mean values ± SEM of 4 oocytes from 4 donors. b Succinate uptake in the absence and presence of 1 mM glutamate in hNaDC3-expressing oocytes (black columns) and mocks (grey columns) as obtained in two independent experiments with 8–10 oocytes for each experimental condition. Uptake of succinate in the absence and presence of glutamate was not significantly different.