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. 2001 Mar 13;98(6):3232–3236. doi: 10.1073/pnas.051624098

Figure 1.

Figure 1

Cancer risk in BRCA1 carriers–survival analysis according to RAD51 genotype. RAD51-135C +- heterozygotes for the RAD51-135C polymorphism. RAD51-135wt (wild type) − homozygous normal (GG) at nucleotide 135. (A) Fraction of BRCA1 carriers remaining free of both breast and ovarian cancer. For RAD51-135C heterozygotes, HR = 1.18 (NS). (B) Fraction of BRCA1 carriers remaining free of breast cancer. For RAD51-135C heterozygotes, HR = 1.16 (NS). (C) Fraction of BRCA1 carriers remaining free of ovarian cancer. For RAD51-135C heterozygotes, HR = 1.28 (NS).