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. 2010 Jun 25;108(Suppl 1):4531–4538. doi: 10.1073/pnas.1000098107

Fig. 1.

Fig. 1.

Schematic depiction of metabolic fate of dietary polyphenols in the human–microbial superorganism. Within the colonic compartment, the microbial bioconversion pathways of naringenin are depicted. Within the host, dietary polyphenols and their microbial bioconversion products successively undergo liver phase I and II metabolism, absorption in the systemic circulation, interaction with organs, and excretion in the urine.