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Knockdown of IL-6 signaling suppresses cell growth. (A) DU145 cells were transfected with siRNA specific to IL-6R and gp130 as indicated. GFP siRNA was used as a control. The cells were counted after 2 days following the transfection. (B) Expression of gp130 and IL-6R mRNA was determined by RT-PCR. Asterisks (*) indicate statistical significance.
