Figure 1.
Schematic representation of hairpin polyamides with increased DNA-binding affinity caused by different γ-turn units. Hairpin polyamides targeted to DNA sequence 5′-TGGTCA-3′ are shown as ball-and-stick models. Ball-and-stick representation legend: black and white circles represent N-methylimidazole and N-methylpyrrole units, respectively, half-circles represent γ-aminobutyric acid, white diamonds represent β-alanine units, and half-circles containing a cross represent 3-(dimethylamino)-1-propylamine (Dp) as tail.
