Figure 7.

(A) Chemical structures and ball-and-stick models of matched and mismatched polyamides 20–23, targeted to DNA sequence 5′-AGAACA-3′. (B) Inhibition of DHT-induced PSA and KLK2 expression by 20–23 measured by quantitative real-time RT-PCR.

(A) Chemical structures and ball-and-stick models of matched and mismatched polyamides 20–23, targeted to DNA sequence 5′-AGAACA-3′. (B) Inhibition of DHT-induced PSA and KLK2 expression by 20–23 measured by quantitative real-time RT-PCR.