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. 2011 Mar 24;7(3):e1002023. doi: 10.1371/journal.pcbi.1002023

Figure 5. Correlating the fluctuograms of subtilisin with co-evolution.

Figure 5

The calculated hit rates (Inline graphic's) and coverages (Inline graphic's) by using Criterion-A, (eq.(2)). (a) Inline graphic's from the apo fluctuogram. (b) Inline graphic's from the Ca2+-bound fluctuogram. Hit rates achieved by randomly picking the same numbers as the selected residues based on Inline graphic = 8 are shown for comparison. The profiles correspond to other Inline graphic values are quantitatively close. (c) Inline graphic's from the apo fluctuogram. (d) Inline graphic's from the Ca2+-bound fluctuogram.