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. 2011 Mar 24;7(3):e1001346. doi: 10.1371/journal.pgen.1001346

Figure 1. Dopamine biosynthetic pathway and calculation of the avoidance index.

Figure 1

(A) Dopamine biosynthetic pathway and enzymes (blue) with their inhibitors (red). TH converts tyrosine to L-DOPA, and then DDC converts L-DOPA to dopamine. AMPT is an inhibitor of TH, and HBH is an inhibitor of DDC. See text for the abbreviations. (B) Formulas for AILow and AIHigh. AI values: 1, all flies resided in the intermediate temperature region; 0, all flies distributed evenly between the intermediate and the other regions; −1, all flies distributed in the low or high temperature region.