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. 2011 Mar 24;6(3):e14767. doi: 10.1371/journal.pone.0014767

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Holder et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Viral yield in time for the A/Brisbane/59/2007 (H1N1) WT (filled circles) and H275Y mutant (open circle) strains. Linear fits on the log-linear graph determine the rates of exponential growth, , for the WT (solid line) and H275Y mutant (dashed) strains, as well as the rates of viral titer decay (dotted). The decay rate, which is assumed to be the rate of viral infectivity loss, , was found to be for both strains.

Inline graphic — Viral yield in time for the A/Brisbane/59/2007 (H1N1) WT (filled circles) and H275Y mutant (open circle) strains. Linear fits on the log-linear graph determine the rates of exponential growth, , for the WT (solid line) and H275Y mutant (dashed) strains, as well as the rates of viral titer decay (dotted). The decay rate, which is assumed to be the rate of viral infectivity loss, , was found to be for both strains.