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. 2011 Mar 24;6(3):e18204. doi: 10.1371/journal.pone.0018204

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von Kleist et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The figure shows the outcome of 500 simulations for the proposed induction-maintenance strategy (blue line) and for the conventional HAART therapy (red line), respectively. Dashed lines indicate the 95% confidence ranges, calculated using Greenwood's formula. The initial abundance of drug resistant mutants was set to 1% of the population. Other parameter values: = 0.75, = 0.8.

Inline graphic — The figure shows the outcome of 500 simulations for the proposed induction-maintenance strategy (blue line) and for the conventional HAART therapy (red line), respectively. Dashed lines indicate the 95% confidence ranges, calculated using Greenwood's formula. The initial abundance of drug resistant mutants was set to 1% of the population. Other parameter values: = 0.75, = 0.8.