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. 2010 Feb 25;1(1):37–40. doi: 10.1007/s12687-010-0002-4

Table 1.

Expected proportions of compound heterozygotes among affected children of consanguineous parent, P(CH), given some values of F, q, and R(CH), the relative frequency of these compound heterozygotes among non-IBD affected children

F q R(CH) P(CH)
1/8 0.01 0.1 0.007
0.5 0.033
0.05 0.1 0.026
0.5 0.130
1/16 0.01 0.1 0.013
0.5 0.065
0.05 0.1 0.043
0.5 0.214
1/64 0.01 0.1 0.039
0.5 0.193
0.05 0.1 0.076
0.5 0.380