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. Author manuscript; available in PMC: 2011 Mar 25.
Published in final edited form as: Eur Heart J. 2009 Dec 21;31(13):1655–1662. doi: 10.1093/eurheartj/ehp555

Fig. 1.

Fig. 1

Experimental protocols of the isolated rat heart experiments. All hearts were stabilized for 30 min prior to experiments. Control hearts received 30 min of regional ischemia followed by 2 h of reperfusion. Mineralocorticoid receptor (MR) antagonists were given throughout reperfusion starting 5 min before reperfusion. The blockers were given either alone accordingly or 5 min before the MR antagonist treatment, while aldosterone (ALDO) was given together with the MR antagonist. The arrows indicate the times of the biopsies of the left ventricle. ■ = regional ischemia.