Table 1.
Hemodynamic parameters
| baseline | ischemia 5 min | ischemia 15 min | ischemia 29 min | reperfusion 30 min | |
|---|---|---|---|---|---|
| Heart rate (beats/min) | |||||
| Experiments with 30 min ischemia and 4 h reperfusion | |||||
| Control | 248±40 | 243±22 | 247±22 | 239±29 | 235±16 |
| Canrenoate | 256±23 | 250±24 | 246±26 | 242±13 | 222±29 |
| Experiments with 30 min ischemia and 72 h reperfusion | |||||
| Control | 242±26 | 240±22 | 239±40 | 233±26 | 218±29 |
| Canrenoate | 248±22 | 234±29 | 234±24 | 231±24 | 222±24 |
| Mean blood pressure (mmHg) | |||||
| Experiments with 30 min ischemia and 4 h reperfusion | |||||
| Control | 70±11 | 62±13 | 62±13 | 61±13 | 62±11 |
| Canrenoate | 74±15 | 61±4 | 60±2 | 69±7 | 66±7 |
| Experiments with 30 min ischemia and 72 h reperfusion | |||||
| Control | 76±13 | 69±9 | 65±9 | 64±9 | 61±4 |
| Canrenoate | 75±13 | 69±11 | 63±11 | 63±9 | 66±7 |