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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2011 Apr;70(4):281–291. doi: 10.1097/NEN.0b013e31821284e9

Figure 7.

Figure 7

Isoflurane induces a decrease in protein levels of endogenous myosin light chain (MLC) and its activated (phosphorylated) form, MLC-P, in immature primary astroglia. (A, B) Isoflurane treatment at day in vitro (DIV) 4 (3% for 24 hours) causes decreases of approximately 50% and 40% in the protein content of endogenous MLC (A) and its phosphorylated fraction (MLC-P) (B), respectively, when measured at DIV7 (2 days post-treatment) (*p < 0.005; n = 5 per data point). (C) The MLC-P fraction (MLC-P/MLC+MLC-P ratio) remained roughly similar (approximately 50%) in sham control and experimental groups. Experimental cultures were compared with age-matched sham control cultures (noted as 100%). Corresponding representative Western blots are shown in the right panel.

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