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. 2010 Dec 14;28(4):797–811. doi: 10.1007/s11095-010-0333-1

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© The Author(s) 2010

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Fig. 5 — Individual post hoc parameter estimates (grey) and population predicted parameter estimates (black) for total morphine clearance (Cl₁ + Cl₂ for the systematic covariate model and Cl₀ + Cl₁ + Cl₂ for the fixed allometric model), the elimination clearances of the metabolites (Cl ₃ and Cl ₄) and distribution volume of the central morphine compartment (V ₁) versus body-weight for the systematic covariate model (A) and the fixed allometric model (B).

Fig. 5 — Individual post hoc parameter estimates (grey) and population predicted parameter estimates (black) for total morphine clearance (Cl₁ + Cl₂ for the systematic covariate model and Cl₀ + Cl₁ + Cl₂ for the fixed allometric model), the elimination clearances of the metabolites (Cl ₃ and Cl ₄) and distribution volume of the central morphine compartment (V ₁) versus body-weight for the systematic covariate model (A) and the fixed allometric model (B).