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. 2011 Mar 7;17(9):1135–1142. doi: 10.3748/wjg.v17.i9.1135

Table 1.

Effect of octreotide on ulcer index and plasma corticosterone level in chronic mild stressed rats

Groups Parameters
Ulcer index (mm) Plasma corticosterone (μg/dL)
Control 0 ± 0 15.4 ± 1.0
OCT (50 μg/kg) 0 ± 0 17.3 ± 0.7
OCT (90 μg/kg) 0 ± 0 16.0 ± 1.2
CMS 6.4 ± 0.16a 28.4 ± 0.6a
CMS + OCT (50 μg/kg) 2.4 ± 0.06a,b 17.2 ± 0.7b
CMS + OCT (90 μg/kg) 0.6 ± 0.01a,b 20.4 ± 1.1b

Rats were subjected to mild stressors for 21 d; octreotide was given 2 h before the insults or to normal animals. Data are mean of 6-8 rats ± SE.

a,b

P < 0.05 compared to control and chronic mild stress (CMS) groups respectively. For comparisons among treatment groups, one-way ANOVA followed by Tukey-Kramer Multiple Comparisons Test was used. OCT: Octreotide.