Table 1.
Groups |
Parameters |
|
Ulcer index (mm) | Plasma corticosterone (μg/dL) | |
Control | 0 ± 0 | 15.4 ± 1.0 |
OCT (50 μg/kg) | 0 ± 0 | 17.3 ± 0.7 |
OCT (90 μg/kg) | 0 ± 0 | 16.0 ± 1.2 |
CMS | 6.4 ± 0.16a | 28.4 ± 0.6a |
CMS + OCT (50 μg/kg) | 2.4 ± 0.06a,b | 17.2 ± 0.7b |
CMS + OCT (90 μg/kg) | 0.6 ± 0.01a,b | 20.4 ± 1.1b |
Rats were subjected to mild stressors for 21 d; octreotide was given 2 h before the insults or to normal animals. Data are mean of 6-8 rats ± SE.
P < 0.05 compared to control and chronic mild stress (CMS) groups respectively. For comparisons among treatment groups, one-way ANOVA followed by Tukey-Kramer Multiple Comparisons Test was used. OCT: Octreotide.