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. 2011 Mar 7;17(9):1152–1159. doi: 10.3748/wjg.v17.i9.1152

Figure 4.

Figure 4

Tumor formation of HepG2 and HepG2.2.15 cells in vivo. A: The volume of subcutaneous tumors were measured and recorded every 2 d. The difference of tumor growth rate between HepG2 and HepG2.2.15 groups was significant (P < 0.01, Mann-Whithey U test); B: Tumor development in four groups in vivo; C: Expansive growth of tumor. The boundary of tumor and normal tissue is clear [hematoxylin and eosin (HE) stain, × 120]. T: Tumor; H: Liver tissue; D: Fatty changes in liver tissue of HepG2.2.15 groups (HE stain, × 120); E: Lung metastasis in HepG2 injected group (HE stain, × 460) and low power field.