Figure 18.
PNB theranostics in vivo includes the generation and detection of two sequential PNBs: (a) a small PNB is generated (with green pump laser pulse) in zebrafish in a specific cell and detected (with red probe laser pulse) thus sensing the cell; (b) the next, bigger PNB (generated with the second pulse of higher energy) destroys the cell, while optical scattering of the 2nd PNB guides the destruction; (c) fluorescent image of the embryo shows prostate labeled cancer cells scattered through its body [96].