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. Author manuscript; available in PMC: 2011 Mar 25.
Published in final edited form as: AIDS. 2009 Mar 13;23(5):631–636. doi: 10.1097/QAD.0b013e328327964f

Table 2.

Incidence rates, incidence rate ratio, hazard ratio and adjusted hazard ratios for risk factors for tuberculosis.

Tuberculosis cases Person-years Incidence rate (95% CI) per 100 person-years Incidence rate ratio (95% CI) Hazard ratio (95% CI) Adjusted hazard ratio (95% CI)
Total 267 4287 6.2 (5.5–7.0)
Sex
 Female 198 3468 5.7 (5.0–6.6) REF REF REF
 Male 68 814 8.3 (6.5–10.6) 1.46 (1.09–1.94) 1.46 (1.11–1.92) 1.22 (0.91–1.62)
Clinic location
 Urban 192 3403 5.6 (4.9–6.5) REF REF REF
 Rural 75 883 8.5 (6.8–10.6) 1.51 (1.13–1.98) 1.51 (1.16–1.98) 1.36 (1.02–1.81)
Age at baseline visit (years)
 17–29 62 1325 4.7 (3.6–6.0) REF REF REF
 30–39 125 1992 6.3 (5.3–7.5) 1.34 (0.98–1.85) 1.34 (0.98–1.82) 1.35 (0.99–1.83)
 >39 80 965 8.3 (6.7–10.3) 1.77 (1.26–2.51) 1.77 (1.28–2.48) 1.59 (1.12–2.26)
CD4 cell count at baseline visit (cells/μl)
 <100 64 598 10.7 (8.4–13.7) REF REF REF
 100–199 64 916 7.0 (5.5–8.9) 0.65 (0.45–0.94) 0.65 (0.46–0.93) 0.68 (0.48–0.96)
 200–349 59 1125 5.2 (4.1–6.8) 0.49 (0.34–0.71) 0.49 (0.34–0.69) 0.40 (0.27–0.57)
 >349 80 1649 4.9 (3.9–6.0) 0.45 (0.32–0.64) 0.45 (0.33–0.63) 0.35 (0.24–0.50)
IPT and HAART history
 Naive 200 2815 7.1 (6.2–8.2) REF REF REF
 HAART only 44 952 4.6 (3.4–6.2) 0.65 (0.46–0.91) 0.62 (0.44–0.87) 0.36 (0.25–0.51)
 IPT only 22 427 5.2 (3.4–7.8) 0.73 (0.44–1.13) 0.71 (0.45–1.10) 0.87 (0.55–1.36)
 IPT and HAART 1 93 1.1 (0.2–7.6) 0.15 (0.004–0.85) 0.14 (0.02–1.03) 0.11 (0.02–0.78)

CI, confidence interval; HAART, highly active antiretroviral therapy; IPT, isoniazid preventive therapy.