Table 1.
Expression and activation of matriptase in human skin disorders
| Specimen | Description | No. of Cases | M69 Positive | M32 Intensity | M19 Intensity |
|---|---|---|---|---|---|
| 1 | IDN | 8 | 5/8 | ++++ | ++++ |
| 2 | Blue nevus | 1 | 0/1 | +++ | +++ |
| 3 | Seborrheic keratosis | 5 | 1/5 | ++ | ++ |
| 4 | Skin tag | 4 | 2/4 | ++ | ++ |
| 5 | Wart | 1 | 0/1 | + | + |
| 6 | EC | 8 | 8/8 | +++ | +++ |
| 7 | Pityriasis rosea | 1 | 1/1 | ++++ | ++++ |
| 8 | Actinic keratosis | 1 | 1/1 | ++++ | ++++ |
| 9 | Sebaceous hyperplasia | 1 | 1/1 | ++++ | ++++ |
| 10 | Folliculitis | 1 | 1/1 | ++++ | ++++ |
| 11 | Natural killer cell lymphoma with skin metastasis | 1 | 1/1 | +++ | +++ |
| 12 | Keloid scar | 1 | 0/1 | ++++ | + |
| 13 | Compound nevus | 1 | 0/1 | + | + |
| 14 | IDN and ruptured EC | 2 | 2/2 | +++ | +++ |
| 15 | Prurigo nodularis | 1 | 1/1 | +++ | +++ |
| 16 | Chronic eczema | 1 | 1/1 | ++++ | ++++ |
| 17 | Pilar sheath acanthoma | 1 | 1/1 | ++++ | ++++ |
| 18 | Tophi | 1 | 1/1 | +++ | +++ |
| 19 | Parakeratosis | 1 | 1/1 | ++++ | ++++ |
| 20 | Drug eruption | 1 | 1/1 | +++ | +++ |
| 21 | Melanocyte nevus | 1 | 0/1 | ++ | ++ |
| 22 | ALHE | 1 | 0/1 | ++ | ++ |
| 23 | Granuloma | 1 | 0/1 | ++ | ++ |
| Total | 45 | 29/45 | 45/45 | 45/45 |
IDN, intradermal nevus; EC, epidermal cyst; ALHE, angiolymphoid hyperplasia with eosinophilia.