Table 1.
SNP | Familial PD GWAS7 | 1st NIA PD-GWAS10 | 2nd NIA PD-GWAS9 | Milan, Italy cohort | Meta-analysis | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
n | OR | P-value | n | OR | P-value | n | OR | P-value | n | OR | P-value | OR | P-value | |
rs1564282 | 1728 | 1.70 | 5.9 × 10−6 | 505 | 1.55 | 0.047 | 1166 | 1.34 | 0.033 | 1379 | 1.32 | 0.0497 | 1.48 | 3.97 × 10−8a |
Each OR reflects the effect of the minor (T) allele, which has a frequency of ∼11% in the overall sample.
aAchieves genome-wide significance.