Table 3.
Cox regression analysis for an incident CVD event (coronary event, stroke, peripheral vascular event) and progression in renal status (defined as any increase in albuminuria level or progression to ESRD)
| Incident CVD event |
Progression in renal status |
|||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (years) |
1.06 (1.04–1.08) |
<0.001 |
1.00 (0.99–1.02) |
0.81 |
| Male sex |
1.11 (0.79–1.54) |
0.55 |
2.01 (1.47–2.76) |
<0.001 |
| HbA1c (%) |
1.06 (0.95–1.18) |
0.32 |
1.41 (1.30–1.53) |
<0.001 |
| Total cholesterol (mmol/L) |
1.26 (1.10–1.45) |
0.001 |
1.19 (1.04–1.37) |
0.01 |
| eGFR (mL/min/1.73 m2) |
0.99 (0.98–0.99) |
<0.001 |
1.00 (0.99–1.01) |
0.88 |
| History of smoking |
1.45 (1.20–1.59) |
0.001 |
1.20 (0.92–1.41) |
0.15 |
| Antihypertensive medication |
0.43 (0.31–0.71) |
<0.001 |
0.58 (0.42–0.81) |
0.001 |
| PP (per 10 mmHg) | 1.22 (1.10–1.34) | <0.001 | 1.00 (0.89–1.12) | 0.96 |
Variables are from baseline.
eGFR, estimated glomerular filtration rate; HR, hazard ratio.