Table 4.
Cox regression analysis for an incident CVD event (coronary event, stroke, peripheral vascular event) in patients by albuminuria status at baseline
| CVD event | ||||||
|---|---|---|---|---|---|---|
| Normoalbuminuria | Microalbuminuria | Macroalbuminuria | ||||
| HR (95% CI) | P value | HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (years) | 1.08 (1.04–1.11) | <0.001 | 1.09 (1.05–1.14) | <0.001 | 1.04 (1.01–1.07) | 0.009 |
| Male sex | 1.24 (0.67–2.28) | 0.49 | 1.12 (0.43–2.95) | 0.82 | 1.15 (0.67–1.98) | 0.68 |
| HbA1c (%) | 1.14 (0.88–1.47) | 0.33 | 1.29 (0.95–1.76) | 0.11 | 1.04 (0.89–1.22) | 0.61 |
| Total cholesterol (mmol/L) | 1.44 (1.05–1.98) | 0.02 | 0.92 (0.55–1.52) | 0.73 | 1.24 (1.02–1.52) | 0.03 |
| eGFR (mL/min/1.73 m2) | 0.99 (0.97–1.01) | 0.23 | 1.01 (0.99–1.03) | 0.31 | 0.99 (0.98–1.00) | 0.046 |
| History of smoking | 1.52 (1.10–1.74) | 0.02 | 1.26 (0.15–1.70) | 0.52 | 1.31 (0.84–1.59) | 0.17 |
| Antihypertensive medication | 0.50 (0.27–0.95) | 0.03 | 0.69 (0.26–1.82) | 0.46 | 0.96 (0.23–4.10) | 0.96 |
| PP (per 10 mmHg) | 1.31 (1.07–1.61) | 0.009 | 1.41 (1.04–1.93) | 0.03 | 1.18 (1.03–1.38) | 0.02 |
Variables are from baseline.
eGFR, estimated glomerular filtration rate; HR, hazard ratio.