Table 2.

ORs and 95% CI of PD according to baseline diabetes status and disease duration^*

	Diabetes		Diabetes duration (years)
	No	Yes	None	<10	≥10	P for trend
All Parkinson diagnoses since 1995
All participants
Number of PD patients	1,393	172	1,393	88	66
OR (95% CI)	1.0	1.41 (1.20–1.66)	1.0	1.11 (0.89–1.38)	1.75 (1.36–2.25)	<0.0001
Excluding participants with stroke, heart disease, cancers, and poor/fair health
Number of PD patients	952	79	952	40	30
OR (95% CI)	1.0	1.34 (1.06–1.69)	1.0	1.00 (0.73–1.38)	1.80 (1.25–2.60)	0.008
Parkinson diagnoses between 1995 and 1999
All participants
Number of PD patients	465	52	465	25	23
OR (95% CI)	1.0	1.31 (0.97–1.75)	1.0	0.97 (0.64–1.45)	1.85 (1.21–2.83)	0.02
Excluding participants with stroke, heart disease, cancers, and poor/fair health
Number of PD patients	328	27	328	12	12
OR (95% CI)	1.0	1.34 (0.90–2.00)	1.0	0.87 (0.49–1.56)	2.12 (1.18–3.78)	0.05
Parkinson diagnosis after 2000
All participants
Number of PD patients	928	120	928	63	43
OR (95% CI)	1.0	1.46 (1.20–1.77)	1.0	1.18 (0.91–1.53)	1.70 (1.25–2.31)	0.001
Excluding participants with stroke, heart disease, cancers, and poor/fair health
Number of PD patients	624	52	624	28	18
OR (95% CI)	1.0	1.33 (1.00–1.78)	1.0	1.07 (0.73–1.56)	1.64 (1.02–2.63)	0.06

*Adjusting for age, sex, race, education, smoking, coffee, BMI, and physical activity. The numbers of participants without PD for the overall analyses were 265,658 (no diabetes), 21,439 (diabetes), 14,280 (diabetes <10 years), and 6,255 (diabetes duration ≥10 years). For the analysis excluding stroke, heart disease, cancers, and poor/fair health, the numbers were 203,299, 11,393, 7,878, and 3,030, respectively.